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Wednesday, February 29, 2012

Dilemma of the male breast enlargement- Gynaecomastia


The term ‘gynaecomastia’ is derived from the word Greek 'gynaik'-meaning woman and 'mastos' meaning breast. Gynaecomastia is an unusual enlargement of the male breast whereby the breast begins to appear as a female breast and embarrasses the person who develops this condition. Enlargement of the male breast is quite common and affects up to 50-60% of males. Gynaecomastia is usually a benign condition but sometimes it may be the sign of underlying diseases and can happen at any age.

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Gynaecomastia- why does it occur?
In general gynaecomastia results from an imbalance of the circulating sex hormone or the way in which the body tissues respond to these hormones. The circulating sex hormones in the male body may be affected by a number of factors. Sometimes the condition appears soon after birth and this happens from the circulating female hormones that pass from mother to child. Pubertal and adolescent boys often present with gynaecomastia. The changing hormonal patterns besides other factors lead to an increase in the breast size and cause them to be emotionally distressed.  Gynaecomastia resulting from hormonal changes occurs in a number of medical condition like aging, hypogonadism (reduced testosterone production), hormone producing tumors or cancers, hyperthyroidism and failure of organs like liver or kidneys. Male hormones are also lowered in malnutrition and starvation resulting in gynaecomastia. Body builders and athletes commonly resort to available steroids to increase their stamina and muscle mass. However this can lead to excess testosterone which is converted to estrogen a feminizing hormone that results in Gynaecomastia. The advent of fast food, beverages and high calorie snacks has led to a large number of the population becoming obese. Along with obesity the breast size often increases from fat deposition leading to gynaecomastia. A large number of drugs or medications like Digoxin, Frusemide, Spironolactone, etc are capable of causing Gynaecomastia as a side effect. While most of these conditions result in Gynaecomastia affecting both breast, enlargement of only one breast may also occur. In such cases one should specifically rule out the start of cancer or malignancy and other diseases. Pollutants such as lead can add to an increased risk of Gynaecomastia. In about 20 to 25% of patients with gynaecomastia there is no detectable cause.

 Gynaecomastia – Where do we start?
Once a proper history and thorough clinical examination is done, your surgeon may ask for a few investigations to confirm the diagnosis. Blood test will help to rule out kidney, liver or thyroid disease. Evaluations of hormonal levels may be needed if feminizing syndromes are suspected. Other tests like ultrasonography and mammography may be asked for if a definite breast disease is though off. Sometime a biopsy or fine needle aspiration cytology (FNAC) may be carried depending on the case. If no disease is suspected as in pubertal gynaecomastia or asymptomatic one, no further tests are needed but the patient can be reevaluated after 6 months.

For physiological Gynaecomastia as in newborns and pubertal gynaecomastia the individual and parents need to be reassured that this condition is temporary and will most likely go away. These cases should be reevaluated every six months. During puberty there is a transient increase in the estradiol concentration and hence pubertal gynaecomastia starts at 10 to 12 years. However it generally regresses over one to two years and uncommonly persists over 17 years. If the gynaecomastia is painful and persisting after two years then surgical removal must be considered. Markedly obese individual who have gynaecomastia should undergo weight reduction, diet and exercise regimes. Sometimes Bariatric Surgery may help when diet and exercises fail. Though bariatric surgery will help to reduce the weight, in some individuals the breast tissue will begin to sag down as the skin fails to contract. These cases will need plastic surgical intervention for treating their gynaecomastia. If a specific underlying cause like those discussed previously is identified, it should be addressed. In hormonal imbalances, hormonal manipulation such as testosterone replacement or anti estrogens may be needed. Medical treatment of gynaecomastia includes Clomiphene- an anti estrogen, Tamoxifen, Danazol, Testolactone and others. However the success rates are variable and a large number of side effects have been reported in the case of these drugs-rashes, nausea, visual problems, epigastric discomfort, weight gain, acne, muscle cramps, fluid retention, abdominal liver function tests, vomiting, edema and worsening of hypertension.

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Gynaecomastia- How can the plastic surgeon help?
The plastic surgeon will first evaluate which tissue is contributing to the breast enlargement- gland fat or skin excess, and then decide on the mode of treatment. In individuals who exercise  a lot or one actively involved in body building , the pectoral muscle underlying  the breast area increases in size and  can mimic a Gynaecomastia though the actual breast size in normal. Sometimes the regions of the areola and nipple are enlarged in size appearing as puffy nipples, while the rest of the breast area is normal. In some individuals the Gynaecomastia is a result of rapid glandular enlargement. In obese patients Gynaecomastia often occurs from an increase in the breast fat (also called Lipomastia). Excess skin can hang loosely and give an appearance of Gynaecomastia in some patients. In most patients there is often a combination of these possibilities. Once we know the cause, a treatment plan can be chalked out.  If the glandular element is responsible an excision or removal through a cosmetically placed scar will be carried out.  Sometimes fat will be the culprit causing breast enlargement.  In such cases Liposuction or removal of fat using a canula or tube through a small opening with the help of a suction machine is carried out.  When skin excess leads to sagging of the breast, the skin will to be removed. Often a combination of these problems exists and the treatment options will be added up.
The patient is usually admitted a day prior if the surgery is planned under general anesthesia.  The anesthetist will review the patient's fitness for this procedure.  Small sized lesion can be removed under local anesthesia.  Once the patient is put to sleep, the surgeon will make a small incision (1 cm) near the breast area.  He will then introduce a canula (Metal tube) to inject a special fluid and then apply suction force to suck the fat out.  Once the appearance is pleasing and symmetrical on both sides, he will evaluate if excess skin is present.  If so then the skin will be removed by a cosmetically placed incision.  If after removing the fat the surgeon finds that the glandular element is still present, he will remove it in addition to the skin and fat excess.  Postoperatively moderate pain can be expected which can be treated with analgesics.  Antibiotics are given to avoid infection.  Some bruising, redness and edema are expected, but they usually settle over few weeks.  A pressure garment must be worn for three months or more as directed by the surgeon.  The patient is discharged on the same evening of surgery or after a few days depending on the nature and extent of surgery.  Smoking should be strictly avoided and exercise regimens must be delayed for 6 weeks or more. Weight lifting and heavy exercises must be avoided for 3 months.  As with any surgery a few risks are associated with gynaecomastia surgery- infection, haematoma (blood collection), Seroma (Serum collection), operated site asymmetry, uneven contours, scars, sensory changes, persisting pain and swelling.  Fortunately these risks are not common and the surgeon takes utmost care to prevent them.  Sometimes an additional touch up procedure may be needed to correct minor residual defects, especially when a combination of procedures is carried out.   

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A large number of individuals with gynaecomastia suffer from cosmetic problems as well as psychological issues.  Young boys and men avoid exposing their chest while swimming or otherwise for fear of being ridiculed. Some even wear tight undergarments and loose outer clothing to mask their breast enlargement. Sometimes parents are distressed by the growing breast in their male children and wonder if they are facing gender issues. Plastic surgery helps to correct the gynaecomastia thereby providing superior cosmetic results.  Patients are able to wear tight fashionable clothing and interact with their peers in different social circumstances.  Post surgery patients have an increased self confidence, good body image and feel better psychologically. Creating awareness about this simple condition is necessary in our society and making the treatment available to all sections of society should be an important agenda of any health program.

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Monday, August 22, 2011

Face Burns

Dear doctor,

Sunday evening my Dad was going to barbeque dinner. There was a leak in the propane tank and there was a flash when he lit the bbq that burned his arms, hands, legs, and face. His hair caught on fire, most of his beard and hair is now gone. Eyelashes and eyebrows are gone as well. He was immediately taken to the ER where they gave him morphine for the pain. This made him vomit and his blood pressure dropped to 58/27. They intubated  him as a precautionary measure and his blood pressure was stabilized. They then moved him to a burn unit in a hospital in SF.

After examining him that night, they said that most of his burns are 1st and 2nd degree. They extubated him late Monday morning and lifted his diet restrictions. Their main concern is infection at this point and his left leg. This area saw the worst damage and they are observing him for 2-3 days to see if he will need surgery.

I read your information on 2nd degree burns and feel that it was extremely well written and understandable for the lay person. Thank you so much for that. The history with my Dad is that he had a staphylococcus infection 4 years ago and endocarditis. He had 50% damage to his heart at that time due to a previous heart attack and the damage from the infection. He had a quadruple bypass 10 years ago and as of the last appointment a month ago the bypasses  are holding. They did say that he is in the beginning stages of liver failure last month as well as congestive heart failure. He is 62 years old.

His blood pressure has been holding steady after that initial drop and he said that he isn't in any pain right now. He is an 8 hour drive away from me right now and they tell me that he is stable, but I can't help but feel that any surgery on him at this point would be very rough on him. Today is the second day of observation and I am planning on heading down to be with him either later today or tomorrow. 

My question is, are my concerns warranted? I feel silly because they say he is stable and to not come, but my gut tells me otherwise. I'm sure by the time you read this I will already be there; I guess I just wanted some reassurance. I am worried that his previous health issues
will make this current trauma worse.

Sorry to take up your time, I just found a lot of comfort in your posts and hoped you might have a thought or two.

Sincerely,
Lori



Dear Ms. Lori,

Thank you very much for you question. I am sorry to hear that your father had a burn accident. We are sorry for the delay in replying because we have a lot of queries waiting. The superficial loss of hair is not significant since one can have the hair burnt and lost from the fire and heat, though the skin may not be burnt. Some patients react to morphine by vomiting and lowering of the blood pressure this usually gets controlled once corrective measures or medication are given.

That he was intubated appears more of a prophylactic measure since they extubated him within 24 hours and he appears to be stable. Also the fact that the BbQ must likely have been in an open space means that inhalation injury to the lungs are unlikely. Most of his burns were 1st and 2nd degree burns- as you said- 1st degree burns- should not be of any worry- it’s like sunburn and will heal quickly. For the 2nd degree burn areas it will depends on whether they are superficial or deep. From what you describe and by the history I feel it may be a 2nd degree superficial burn which will heal, but we can’t be sure till we examine the burn itself.
In view of his medical illnesses prophylactic antibiotic coverage should be discussed with his treating surgeon and may be a good idea. A physician should also be involved to manage his medical problems (heart and liver problems). Finally the area of the deep burn if present may be small as I presume from your description. Good timely analgesics should be helpful along with local dressings and care of the wound. An ophthalmologist should also check his eyes to rule out any burn injury to the eye which is quite common in patients with face burns.

I hope he recovers quickly and that he may not need any surgery by God’s grace.

With best regards,
asktheburnsurgeon+

Lori wrote to us again…..

Dear doctor,
Thank you so much for your response. You are correct that the bbq was in an open area. He was lucky because he shut his eyes and mouth before there was any damage to his lungs or eyes.
An update on my Dad. The enzyme cream that they used to eat away at the dead tissue is working really well. They do not believe that surgery will be necessary for now. He is continuing with the debridment baths every day for now, which have become very painful for him, but they are working. There has even been talk about discharge this weekend. We are so grateful that he is progressing so well. Seeing the other patients in the burn unit made me realize how lucky he was.
Thank you again for your response. Of course you can put this up on your website. The posts on there helped me at a time when I had no idea which way this would go. If our story can help someone else, please use it.
Thank you again,
Lori



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